Successful pregnancy following the transfer of vitrified blastocyst which developed from poor quality embryos on day 3
نویسندگان
چکیده
BACKGROUND The selection of pre-embryos for transferred is based on morphological appearance. But some poor quality cleaved embryos also can be cultured to the blastocyst stage and implanted. OBJECTIVE To assess the clinical pregnancy outcomes of blastocyst transfer which developed from poor quality embryos. MATERIALS AND METHODS A total of 109 cleaved embryos with poor quality were cultured to day 5/day 6 and 27 (24.8%) blastocysts were collected from the 15 cycles/patients undergoing conventional IVF. All the blastocysts were cooling with fast-freezing. Then the blastocysts were warmed for transfer. RESULTS All of 25 vitrified blastocysts (92.6%) survived after warming and were transferred to 15 patients. Five of the women became pregnant. CONCLUSION Our results suggest that vitrified human day 5/day 6 blastocyst transfer which develop from poor quality embryo at day 3 can contribute to increasing cumulative pregnancy rates in assisted reproduction.
منابع مشابه
Inm-5: Outcomes of Human Vitrified Embryos Transfer
The techniques of cryopreservation let embryos which cannot be immediately transferred to the patient be stored for future use. The first successful pregnancy after transfer of cryopreserved human embryos was described in 1983 by Trounson et al. and the first birth after cryopreservation was later reported in 1984 by Zeilmaker et al.). The technique has rapidly been applied in most in-vitro fer...
متن کاملClinical outcomes of vitrified-thawed embryo transfer using a pull and cut straw method
OBJECTIVE To compare the clinical outcomes of patients with vitrified-thawed embryos transferred using either the 0.25 mL straw method and the pull and cut straw (PNC) method. To evaluate the clinical outcomes of patients with transferred embryos that underwent assisted hatching at the cleaved embryo (day 3) or the blastocyst (day 5) stage. METHODS The study population consisted of women who ...
متن کاملLive birth after transfer of a twice-vitrified warmed blastocyst that had undergone trophectoderm biopsy.
A 28-year-old patient presented for preimplantation genetic screening (PGS) for family balancing utilizing previously vitrified blastocysts and day-2 embryos. To synchronize endometrial development with the embryos to be transferred, five embryos vitrified on day 2 were warmed 3 days prior to scheduled transfer. Three of them developed to 8-, 8- and 7-cell stages, respectively, and were biopsie...
متن کاملCulturing surplus poor-quality embryos to blastocyst stage have positive predictive value of clinical pregnancy rate
BACKGROUND Clinical reproductive centers produce large amounts of surplus poor-quality embryos annually, how to maximize the use of these embryos, and which of them have the potential to develop into blastocyst stage and influencing factors were lack of systematic research. OBJECTIVE To investigate the fate of surplus poor-quality embryos which were cultured to obtain blastocyst, determine th...
متن کاملEfficacy of oocyte vitrification combined with blastocyst stage transfer in an egg donation program.
BACKGROUND A successful oocyte vitrification program is important for women with various indications for assisted reproduction technology. The objective of this study was to report the outcome of vitrification of oocytes, obtained through an oocyte donation program, by evaluating the embryo development, pregnancy and implantation rates (IRs) after blastocyst transfer. METHODS A total of 1098 oo...
متن کامل